Research

We invent reactions that unlock static molecular compartments, regions of structure whose reactivity, conformation, or electronic character is limited. We then deploy that chemical space toward photoswitchable materials and small molecule therapeutics.

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The program is organized around two platforms: iron-catalyzed and metal-free methods for congested C–heteroatom bond construction, and heterocyclic rearrangements that generate amino Stenhouse photoswitches.